The wildest and most scenic section of the river is in the vicinity of the Grey Preserve, where arching trees often form a jungle-like canopy. Fragrant spider lilies greet paddlers in the warmer months. Below the preserve, the river flows through the town of New Port Richey and it is more of an urban paddling trail. Weekends and holidays in this lower section can be busy with boat traffic. Submerged logs are the biggest hazard for swimmers and paddlers since the water is dark. Due to its accessibility and scenic nature, the Pithlachascotee is one of Florida's state-designated paddling trails.